Title: What should I take with Domperidone? Revealing drug combination taboos and hot health topics
Recently, health topics have continued to occupy the hot search list on social media, especially the issue of safe use of drugs, which has triggered widespread discussions. Among them, "What foods or drugs should not be taken with domperidone" has become one of the most popular medical topics in the past 10 days. This article will combine hotspot data from the entire Internet to provide you with a detailed analysis of the drug contraindications of domperidine.
1. Top 5 health topics in the past 10 days

| Ranking | topic | search volume | Platform |
|---|---|---|---|
| 1 | Domperidine incompatibility | 1,200,000+ | Baidu/Weibo |
| 2 | Helicobacter pylori family transmission | 980,000+ | Douyin/Xiaohongshu |
| 3 | Homemade electrolyte water recipe | 850,000+ | Kuaishou/Bilibili |
| 4 | H1N1 prevention guide | 720,000+ | WeChat/Zhihu |
| 5 | Risks of Melatonin Dependence | 680,000+ | Toutiao/Douban |
2. Basic drug information on domperidine
| Drug name | Main ingredients | Indications | Usual dosage |
|---|---|---|---|
| Morphine | Domperidone | Indigestion/bloating/nausea and vomiting | 10mg/time, 3 times/day |
3. Domperidone incompatibility list (key content)
| Category | specific name | interaction | Hazard level |
|---|---|---|---|
| Drugs | Ketoconazole/erythromycin | Increased risk of cardiotoxicity | ★★★★★ |
| Drugs | Antacids (aluminum magnesium carbonate, etc.) | Reduce drug efficacy | ★★★☆☆ |
| Food | Grapefruit/grapefruit juice | Affect drug metabolism | ★★★★☆ |
| Food | alcoholic beverages | aggravate central depression | ★★★☆☆ |
| Traditional Chinese Medicine | Chinese medicine containing tannins (gallnut, etc.) | Form insoluble matter | ★★☆☆☆ |
4. The correct way to take it as recommended by experts
1.Best time to take:Take it 15-30 minutes before meals. Avoid taking it with food to affect absorption.
2.Suitable for:It can be taken with warm water. It is recommended to remain in an upright position for 30 minutes after taking the medicine.
3.Attention for special groups:Pregnant women and patients with heart disease must strictly follow medical advice. Children under 12 years old are prohibited from using this product.
5. Recent relevant hot events
1. An Internet celebrity was sent to the hospital because of a prolongation of the QT interval after taking mixed doses of domperidone and antibiotics (a hot search on Weibo # Mixed Drugs Danger#)
2. The State Food and Drug Administration released the "Guidelines for the Clinical Application of Gastrointestinal Motility Drugs" (an authoritative document attracting attention)
3. The 315 Party exposed illegal sales of prescription drugs (including domperidone drugs) on online shopping platforms
6. Four principles for safe medication use
1.View the instructions:Focus on the "Drug Interactions" and "Contraindications" chapters
2.Interval between doses:When multiple medications need to be taken at the same time, it is recommended to take them at least 2 hours apart.
3.Consult a pharmacist:For complex medication situations, it is recommended to consult a licensed pharmacist at the pharmacy.
4.Monitoring reactions:If abnormal symptoms such as palpitations and dizziness occur after taking the medicine, seek medical attention immediately
Conclusion:As public health awareness increases, the topic of rational drug use continues to receive attention. Domperidine is a commonly used gastric medicine, and its incompatibility is related to medication safety. It is recommended to collect the contents of this form and forward it to those who need it. The National Health Commission will launch the "Safe Medication Month" event in the near future. More authoritative information can be found through the "Rational Medication" official mini program.
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